B7-33

Description

B7-33

Single-chain relaxin analog studied for fibrosis and cardiovascular research.

B7-33 is an experimental peptide designed to mimic relaxin-2, functioning as a selective agonist for the RXFP1 receptor. Developed as a simplified, single-chain version of the natural hormone relaxin, it offers easier synthesis while maintaining many of relaxin’s key biological activities observed in preclinical research. The compound has drawn considerable scientific attention due to its potential role in reducing fibrosis, protecting heart tissue, promoting blood vessel dilation, and supporting tissue remodeling. Studies have demonstrated encouraging results in animal models of cardiac fibrosis, heart injury, lung fibrosis, and related regenerative processes.

Primary areas of research focus include:
– Mechanisms involved in anti-fibrotic activity
– Heart health and structural changes in cardiac tissue
– Tissue healing and regrowth
– Blood vessel function and vasodilatory effects
– Signaling pathways associated with the RXFP1 receptor