Description
Thymosin Beta-4
Thymosin Beta-4 (Tβ4) is a naturally occurring peptide with regenerative properties that contribute to cell movement, tissue repair, inflammation modulation, and wound healing. A key function of Tβ4 is its regulation of actin, which supports more effective cellular migration and the restoration of injured tissues. Due to these capabilities, it is actively researched for potential benefits in muscle recovery, healing of tendons and ligaments, skin regeneration, and protection of cardiovascular tissues. Tβ4 is also the full-length molecule from which TB-500—a truncated version commonly used in scientific studies—is derived.
Also known as: TB-4, Tβ4, Timbetasin
• Status: Currently in Phase II/III clinical trials for wound healing and dry eye conditions. Evidence based on human trials.
• Common dosage: 2.5–5 mg administered 2 to 3 times per week via subcutaneous injection; topical application used for eye-related issues.
• Investigated for potential use in wound healing, heart tissue repair, and broader tissue regeneration applications.
• Common dosage: 2.5–5 mg administered 2 to 3 times per week via subcutaneous injection; topical application used for eye-related issues.
• Investigated for potential use in wound healing, heart tissue repair, and broader tissue regeneration applications.





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